Abstract
InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
MeSH terms
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Animals
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Binding Sites
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Calcium Channels / metabolism
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Drosophila
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Drosophila Proteins*
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Eye Proteins / metabolism*
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GTP-Binding Proteins / metabolism
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Photoreceptor Cells, Invertebrate / metabolism*
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Protein Kinase C / metabolism
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Signal Transduction*
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TRPC Cation Channels
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Type C Phospholipases / metabolism
Substances
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Calcium Channels
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Drosophila Proteins
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Eye Proteins
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TRPC Cation Channels
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inaD protein, Drosophila
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transient receptor potential cation channel, subfamily C, member 1
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Protein Kinase C
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Type C Phospholipases
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GTP-Binding Proteins