Squinting at the zebrafish axis

Dev Cell. 2006 Jan;10(1):6-7. doi: 10.1016/j.devcel.2005.11.001.

Abstract

The Nodal family of signaling molecules includes critical intercellular regulators of early vertebrate development. In a recent issue of Nature, maternal transcripts encoding the zebrafish nodal squint were shown to be localized to the future organizer region by the four-cell stage, providing the earliest evidence of embryonic axis asymmetry in the zebrafish embryo.

MeSH terms

  • Animals
  • Body Patterning / physiology*
  • Embryo, Nonmammalian
  • Endoderm
  • Gene Expression Regulation, Developmental
  • Models, Biological
  • Nodal Signaling Ligands
  • Signal Transduction / physiology*
  • Zebrafish / physiology*
  • Zebrafish Proteins / genetics
  • Zebrafish Proteins / metabolism*

Substances

  • Nodal Signaling Ligands
  • Zebrafish Proteins
  • ndr1 protein, zebrafish