Abstract
The Nodal family of signaling molecules includes critical intercellular regulators of early vertebrate development. In a recent issue of Nature, maternal transcripts encoding the zebrafish nodal squint were shown to be localized to the future organizer region by the four-cell stage, providing the earliest evidence of embryonic axis asymmetry in the zebrafish embryo.
MeSH terms
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Animals
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Body Patterning / physiology*
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Embryo, Nonmammalian
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Endoderm
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Gene Expression Regulation, Developmental
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Models, Biological
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Nodal Signaling Ligands
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Signal Transduction / physiology*
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Zebrafish / physiology*
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Zebrafish Proteins / genetics
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Zebrafish Proteins / metabolism*
Substances
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Nodal Signaling Ligands
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Zebrafish Proteins
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ndr1 protein, zebrafish