Protein Family Models for Protein (Select 779794016) - Protein Family Models

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Links from Protein

Items: 6

Select item 4120111.

Members of this family usually also match to Pfam:PF00330. This domain undergoes conformational change in the enzyme mechanism [1]. [1]. 7675781. Steric and conformational features of the aconitase mechanism. Lauble H, Stout CD;. Proteins 1995;22:1-11. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF012897.5
Method:: HMM

Select item 3892212.

new record, indexing in progress

Family Accession:

Select item 3471383.

new record, indexing in progress

Family Accession:

Select item 1789124.

3-isopropylmalate dehydratase small subunit

Date:: 2020-10-26

Family Accession:: NF002458.0
Method:: HMM

Select item 1345445.

3-isopropylmalate dehydratase small subunit

3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate

Date:: 2023-03-01

Family Accession:: 10011702
Method:: Sparcle

Select item 164286.

3-isopropylmalate dehydratase small subunit

Homoaconitase, aconitase, and 3-isopropylmalate dehydratase have similar overall structures. All are dehydratases (EC 4.2.1.-) and bind a Fe-4S iron-sulfur cluster. 3-isopropylmalate dehydratase is split into large (leuC) and small (leuD) chains in eubacteria. Several pairs of archaeal proteins resemble the leuC and leuD pair in length and sequence but even more closely resemble the respective domains of homoaconitase, and their identity is uncertain. The candidate archaeal leuD proteins are not included in the seed alignment for this model and score below the trusted cutoff.