Protein Family Models for Protein (Select 771525501) - Protein Family Models

Select item 4250921.

NAD(P)-binding domain-containing protein

Date:: 2024-08-14

Family Accession:: NF025114.5
Method:: HMM

Select item 4208842.

thioredoxin family protein

Date:: 2024-08-14

Family Accession:: NF024590.5
Method:: HMM

Select item 4169533.

FAD-dependent oxidoreductase

This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. [1]. 8805537. Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase. Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG;. Structure 1996;4:277-286. (from Pfam)

GO Terms:

Molecular Function:: oxidoreductase activity (GO:0016491)

Date:: 2024-10-16

Family Accession:: NF019604.5
Method:: HMM

Select item 4111454.

NAD-binding protein

Date:: 2024-10-16

Family Accession:: NF012299.5
Method:: HMM

Select item 4024985.

new record, indexing in progress

Family Accession:

Select item 4022346.

new record, indexing in progress

Family Accession:

Select item 3968307.

new record, indexing in progress

Family Accession:

Select item 3886368.

new record, indexing in progress

Family Accession:

Select item 3638369.

new record, indexing in progress

Family Accession:

Select item 35656010.

new record, indexing in progress

Family Accession:

Select item 35377711.

new record, indexing in progress

Family Accession:

Select item 34658912.

new record, indexing in progress

Family Accession:

Select item 33644713.

new record, indexing in progress

Family Accession:

Select item 23564814.

alkyl hydroperoxide reductase subunit F

alkyl hydroperoxide reductase subunit F, a flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC

Date:: 2023-03-15

Family Accession:: 11487737
Method:: Sparcle

Select item 15887715.

new record, indexing in progress

Family Accession:

Select item 5282416.

alkyl hydroperoxide reductase subunit F

This enzyme is the partner of the peroxiredoxin (alkyl hydroperoxide reductase) AhpC which contains the peroxide-reactive cysteine. AhpF contains the reductant (NAD(P)H) binding domain (PF00070) and presumably acts to resolve the disulfide which forms after oxidation of the active site cysteine in AphC [1]. This proteins contains two paired conserved cysteine motifs, CxxCP and CxHCDGP.

Gene:: ahpF

GO Terms:

Biological Process:: response to reactive oxygen species (GO:0000302)

Molecular Function:: alkyl hydroperoxide reductase activity (GO:0008785)

Molecular Function:: flavin adenine dinucleotide binding (GO:0050660)

Molecular Function:: NAD binding (GO:0051287)

Date:: 2024-05-15

Family Accession:: TIGR03140.1
Method:: HMM

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