Protein Family Models

chromosome partition protein MukE acts with MukB and MukF to condense the chromosome and allow for segregation during cell division

Date:

2024-02-09

This entry represents a small family of MksE proteins. These proteins are part of MksBEF complex, which primarily function in structural chromosome maintenance [1]. The N-terminal part of MksE is remotely related to the chromosome partition protein MukE and most likely adopts the same structure that consists of two winged helix domains (WHD) [2]. [1]. 35072315. Condensins are essential for Pseudomonas aeruginosa corneal virulence through their control of lifestyle and virulence programs. Zhao H, Clevenger AL, Coburn PS, Callegan MC, Rybenkov VV;. Mol Microbiol. 2022;117:937-957. [2]. 19135891. Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions. Woo JS, Lim JH, Shin HC, Suh MK, Ku B, Lee KH, Joo K, Robinson H, Lee J, Park SY, Ha NC, Oh BH;. Cell. 2009;136:85-96. (from Pfam)

Date:

2024-10-21

Bacterial protein involved in chromosome partitioning, MukE [1]. 10545099. Complex formation of MukB, MukE and MukF proteins involved in chromosome partitioning in Escherichia coli. Yamazoe M, Onogi T, Sunako Y, Niki H, Yamanaka K, Ichimura T, Hiraga S;. EMBO J 1999;18:5873-5884. (from Pfam)

Date:

2024-10-16

Acts with MukB and MukF to condense the chromosome and allow for segregation during cell division

Gene:

mukE

Date:

2021-10-13