Protein Family Models for Protein (Select 739087154) - Protein Family Models

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Items: 6

Select item 4223141.

substrate-binding domain-containing protein

This domain is found in a variety of bacterial periplasmic binding proteins. This domain recognises fructose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). (from Pfam)

Date:: 2024-08-14

Family Accession:: NF024799.5
Method:: HMM

Select item 4118352.

Periplasmic binding proteins and sugar binding domain of LacI family

This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (Pfam:PF00356). [1]. 1583688. 1.7 A X-ray structure of the periplasmic ribose receptor from Escherichia coli. Mowbray SL, Cole LB;. J Mol Biol 1992;225:155-175. [2]. 8638105. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P;. Science 1996;271:1247-1254. (from Pfam)