Protein Family Models for Protein (Select 734884252) - Protein Family Models

Select item 4288381.

Phosphoribosyl-dephospho-CoA transferase MdcG N-terminal domain

This entry represents the N-terminal SH3-like domain from MdcG which is a phosphoribosyl-dephospho-CoA transferase that is involved in the biosynthesis of the prosthetic group of malonate decarboxylase [1]. Malonate decarboxylase from Klebsiella pneumoniae contains an acyl carrier protein (MdcC) to which a 2'-(5' '-phosphoribosyl)-3'-dephospho-CoA prosthetic group is attached via phosphodiester linkage. MdcG catalyses the following reaction: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + apo-[acyl-carrier-protein] = holo-[acyl-carrier-protein] + diphosphate. [1]. 11052675. Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. Hoenke S, Wild MR, Dimroth P;. Biochemistry. 2000;39:13223-13232. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF045234.2
Method:: HMM

Select item 4196102.

phosphoribosyl-dephospho-CoA transferase MdcG domain-containing protein

This entry represents the C-terminal catalytic domain of MdcG, which is a phosphoribosyl-dephospho-CoA transferase that is involved in the biosynthesis of the prosthetic group of malonate decarboxylase [1]. Malonate decarboxylase from Klebsiella pneumoniae contains an acyl carrier protein (MdcC) to which a 2'-(5' '-phosphoribosyl)-3'-dephospho-CoA prosthetic group is attached via phosphodiester linkage. MdcG catalyses the following reaction: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + apo-[acyl-carrier-protein] = holo-[acyl-carrier-protein] + diphosphate. [1]. 11052675. Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase. Hoenke S, Wild MR, Dimroth P;. Biochemistry. 2000;39:13223-13232. (from Pfam)

GO Terms:

Molecular Function:: nucleotidyltransferase activity (GO:0016779)

Date:: 2024-10-16

Family Accession:: NF022087.5
Method:: HMM

Select item 4082153.

new record, indexing in progress

Family Accession:

Select item 3964894.

new record, indexing in progress

Family Accession:

Select item 3552545.

new record, indexing in progress

Family Accession:

Select item 1774556.

malonate decarboxylase holo-ACP synthase

GO Terms:

Molecular Function:: nucleotidyltransferase activity (GO:0016779)

Date:: 2021-08-16

Family Accession:: NF002332.0
Method:: HMM

Select item 1345377.

phosphoribosyl-dephospho-CoA transferase

phosphoribosyl-dephospho-CoA transferase catalyzes the transfer of 2-(5'-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein

Date:: 2015-08-31

Family Accession:: 10011656
Method:: Sparcle

Select item 531658.

malonate decarboxylase holo-[acyl-carrier-protein] synthase

Malonate decarboxylase, like citrate lyase, has a unique acyl carrier protein subunit with a prosthetic group derived from, and distinct from, coenzyme A. Members of this protein family are the phosphoribosyl-dephospho-CoA transferase specific to the malonate decarboxylase system. This enzyme can also be designated holo-ACP synthase (2.7.7.61). The corresponding component of the citrate lyase system, CitX, shows little or no sequence similarity to this family.

Gene:: mdcG

GO Terms:

Molecular Function:: transferase activity, transferring phosphorus-containing groups (GO:0016772)

Date:: 2024-06-14

Family Accession:: TIGR03135.1
Method:: HMM

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