Protein Family Models

DIT1 is involved in synthesising dityrosine [1]. Dityrosine is a sporulation-specific component of the yeast ascospore wall that is essential for the resistance of the spores to adverse environmental conditions. Pyoverdine biosynthesis protein PvcA is involved in the biosynthesis of pyoverdine, a cyclized isocyano derivative of tyrosine [2,3]. It has a modified Rossmann fold [3]. [1]. 8183942. The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine-containing precursor of the yeast spore wall. Briza P, Eckerstorfer M, Breitenbach M;. Proc Natl Acad Sci U S A 1994;91:4524-4528. [2]. 8704959. Novel pyoverdine biosynthesis gene(s) of Pseudomonas aeruginosa PAO. Stintzi A, Cornelis P, Hohnadel D, Meyer JM, Dean C, Poole K, Kourambas S, Krishnapillai V;. Microbiology 1996;142:1181-1190. [3]. 18824174. Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin. Drake EJ, Gulick AM;. J Mol Biol. 2008;384:193-205. (from Pfam)

Date:

2024-10-16

Gene:

pvcA

Date:

2024-02-01

isocyanide synthase family protein similar to Aspergillus fumigatus isocyanide synthase B that is involved in the biosynthesis of isocyanides (or isonitriles), a class of microbial secondary metabolites

Date:

2017-03-02