Protein Family Models

FliO is an essential component of the flagellum-specific protein export apparatus [1]. It is an integral membrane protein that acts as an assembly chaperone for the flagellar protein FliP (Pfam:PF00813). It is crucial, although not strictly required, for efficient FliP assembly and, thus flagellar assembly and function [2]. [1]. 10049367. Components of the Salmonella flagellar export apparatus and classification of export substrates. Minamino T, Macnab RM;. J Bacteriol 1999;181:1388-1394. [2]. 28771474. A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum. Fabiani FD, Renault TT, Peters B, Dietsche T, Galvez EJC, Guse A, Freier K, Charpentier E, Strowig T, Franz-Wachtel M, Macek B, Wagner S, Hensel M, Erhardt M;. PLoS Biol. 2017;15:e2002267. (from Pfam)

Date:

2024-10-16

This short protein found in flagellar biosynthesis operons contains a highly hydrophobic N-terminal sequence followed generally by two basic amino acids. This region is reminiscent of but distinct from the twin-arginine translocation signal sequence. Some instances of this gene have been names "FliZ" but phylogenetic tree building supports a single FliO family.

Gene:

fliO

Date:

2024-05-30

flagellar type III secretion system protein FliO is an essential component of the flagellum-specific protein export apparatus

Date:

2019-06-06