Protein Family Models

This domain is found to the N-terminus of bacterial signal peptidases of the S49 family (Pfam:PF01343) [1,2]. [1]. 15611110. A novel thermostable membrane protease forming an operon with a stomatin homolog from the hyperthermophilic archaebacterium Pyrococcus horikoshii. Yokoyama H, Matsui I;. J Biol Chem 2005;280:6588-6594. [2]. 15205439. Displacements of prohead protease genes in the late operons of double-stranded-DNA bacteriophages. Liu J, Mushegian A;. J Bacteriol 2004;186:4369-4375. (from Pfam)

Date:

2024-10-16

Date:

2024-08-14

This family of archaebacterial proteins, formerly known as DUF114, has been found to be a serine dehydrogenase proteinase distantly related to ClpP proteinases that belong to the serine proteinase superfamily. The family has a catalytic triad of Ser, Asp, His residues, which shows an altered residue ordering compared with the ClpP proteinases but similar to that of the carboxypeptidase clan [1]. [1]. 15752073. Identification and analysis of a new family of bacterial serine proteinases. Pandit SB, Srinivasan N;. In Silico Biol. 2004;4:563-572. (from Pfam)

Date:

2024-11-10

Gene:

sohB

Date:

2021-08-04

S49 family peptidase similar to SppA (Signal peptide peptidase A), which is a membrane-bound serine protease that functions to cleave remnant signal peptides in the membrane left behind by the action of signal peptidases

Date:

2017-02-23