Protein Family Models for Protein (Select 694077831) - Protein Family Models

Select item 4209951.

phage integrase SAM-like domain-containing protein

A family of uncharacterised proteins found by clustering human gut metagenomic sequences [1]. This family appears related to the N-terminal domain of phage integrases. [1]. 20532204. Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families. Ellrott K, Jaroszewski L, Weizhong L, Wooley J, Godzik, A. PLoS Computational Biology, 2010 (from Pfam)

Date:: 2024-10-16

Family Accession:: NF024502.5
Method:: HMM

Select item 4177062.

phage integrase Arm DNA-binding domain-containing protein

The amino terminal domain of bacteriophage lambda integrase folds into a three-stranded, antiparallel beta-sheet that packs against a C-terminal alpha-helix, adopting a fold that is structurally related to the three-stranded beta-sheet family of DNA-binding domains (which includes the GCC-box DNA-binding domain and the N-terminal domain of Tn916 integrase). This domain is responsible for high-affinity binding to each of the five DNA arm-type sites and is also a context-sensitive modulator of DNA cleavage [1]. [1]. 11904406. Arm-site binding by lambda -integrase: solution structure and functional characterization of its amino-terminal domain. Wojciak JM, Sarkar D, Landy A, Clubb RT;. Proc Natl Acad Sci U S A. 2002;99:3434-3439. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: integrase activity (GO:0008907)

Biological Process:: DNA integration (GO:0015074)

Date:: 2024-10-16

Family Accession:: NF020572.5
Method:: HMM

Select item 4140533.

site-specific integrase

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Biological Process:: DNA integration (GO:0015074)

Date:: 2024-08-14

Family Accession:: NF014898.5
Method:: HMM

Select item 4003704.