Protein Family Models

The function of these proteins is unknown. They may possibly be involved in the formation of formate dehydrogenase. [1]. 2170340. Identification and expression of the Escherichia coli fdhD and fdhE genes, which are involved in the formation of respiratory formate dehydrogenase. Schlindwein C, Giordano G, Santini CL, Mandrand MA;. J Bacteriol 1990;172:6112-6121. [2]. 1648557. Genetic evidence that genes fdhD and fdhE do not control synthesis of formate dehydrogenase-N in Escherichia coli K-12. Stewart V, Lin JT, Berg BL;. J Bacteriol 1991;173:4417-4423. (from Pfam)

Gene:

fdhE

Date:

2024-10-16

This HMM describes an accessory protein required for the assembly of formate dehydrogenase of certain proteobacteria although not present in the final complex [1]. The exact nature of the function of FdhE in the assembly of the complex is unknown, but considering the presence of selenocysteine, molybdopterin, iron-sulfur clusters and cytochrome b556, it is likely to have something to do with the insertion of cofactors.

Gene:

fdhE

Date:

2020-04-10

formate dehydrogenase accessory protein FdhE involved in the formation of active formate dehydrogenase, its exact function is unknown

Date:

2015-09-16

Required for the formation of active formate dehydrogenase

Gene:

fdhE

Date:

2020-10-26