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PIG-L family deacetylase
Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyses the second step in GPI biosynthesis [1,2]. [1]. 10085243. Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis. Watanabe R, Ohishi K, Maeda Y, Nakamura N, Kinoshita T;. Biochem J 1999;339:185-192. [2]. 12876312. Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8. Handa N, Terada T, Kamewari Y, Hamana H, Tame JR, Park SY, Kinoshita K, Ota M, Nakamura H, Kuramitsu S, Shirouzu M, Yokoyama S;. Protein Sci. 2003;12:1621-1632. (from Pfam)
PIG-L deacetylase family protein
PIG-L (phosphatidylinositol glycan class L) deacetylase family protein may catalyze the removal of an acetyl group from a specific acetylated substrate
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