Protein Family Models for Protein (Select 556486509) - Protein Family Models

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Links from Protein

Items: 6

Select item 4126841.

This family has been called SPFH [1], Band 7 or PHB domain. Recent phylogenetic analysis has shown this domain to be a slipin or Stomatin-like integral membrane domain conserved from protozoa to mammals. [1]. 10542406. The SPFH domain: implicated in regulating targeted protein turnover in stomatins and other membrane-associated proteins. Tavernarakis N, Driscoll M, Kyrpides NC;. Trends Biochem Sci 1999;24:425-427. [2]. 18267007. Slipins: ancient origin, duplication and diversification of the stomatin protein family. Green JB, Young JP;. BMC Evol Biol. 2008;8:44. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF013324.5
Method:: HMM

Select item 3889432.

new record, indexing in progress

Family Accession:

Select item 3481553.

new record, indexing in progress

Family Accession:

Select item 1429764.

protease modulator HflC

HflK and HflC are paralogs encoded by tandem genes in Proteobacteria, spirochetes, and some other bacterial lineages. The HflKC complex is anchored in the membrane and exposed to the periplasm. The complex is not active as a protease, but rather binds to and appears to modulate the ATP-dependent protease FtsH. The overall function of HflKC is not fully described.

Gene:: hflC

GO Terms:

Cellular Component:: outer membrane-bounded periplasmic space (GO:0030288)

Biological Process:: negative regulation of proteolysis (GO:0045861)

Date:: 2024-06-14

Family Accession:: TIGR01932.1
Method:: HMM

Select item 596315.

protease modulator HflC

protease modulator HflC (high frequency of lysogenization C) is an inner membrane protein and part of the HflCK complex that modulates the protease FtsH