Protein Family Models

The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices. (from Pfam)

Date:

2024-08-14

phosphate ABC transporter permease PstA is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter for phosphate; ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment; the captured solute is delivered to a gated translocation pathway formed by the two TMs

Date:

2019-06-06

Part of an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation

Gene:

pstA

Date:

2022-10-11

This HMM describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise.

Gene:

pstA

Date:

2022-10-11