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BRO family protein
This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription [1]. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins [2]. [1]. 10888617. Evidence for nucleic acid binding ability and nucleosome association of bombyx mori nucleopolyhedrovirus BRO proteins. Zemskov EA, Kang W, Maeda S;. J Virol 2000;74:6784-6789. [2]. 9847359. The genome of Melanoplus sanguinipes entomopoxvirus. Afonso CL, Tulman ER, Lu Z, Oma E, Kutish GF, Rock DL;. J Virol 1999;73:533-552. (from Pfam)
Bro-N domain-containing protein
Bro-N domain-containing protein may bind DNA to influence host DNA replication and/or transcription; may function as an antirepressor
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