Inner membrane-spanning protein YciB (also known as intracellular septation protein A) is a family of proteins which are essential for both normal cell division and bacterial virulence and are believed to play a role in the septation process [1,2,3]. These proteins play a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis [3,4,5,6]. [1]. 8830250. Identification and characterization of ispA, a Shigella flexneri chromosomal gene essential for normal in vivo cell division and intracellular spreading. Mac Siomoin RA, Nakata N, Murai T, Yoshikawa M, Tsuji H, Sasakawa C.;. Mol Microbiol 1996;19:599-609. [2]. 9746567. Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading. Hong M, Gleason Y, Wyckoff EE, Payne SM;. Infect Immun. 1998;66:4700-4710. [3]. 26391555. Escherichia coli inner membrane protein YciB interacts with ZipA that is important for cell division. Badaluddin NA, Kitakawa M;. Genes Cells. 2015;20:956-965. [4]. 26454142. Characterization of inner membrane protein YciB in Escherichia coli: YciB interacts with cell elongation and division proteins. Li G, Badaluddin NA, Kitakawa M;. Microbiol Immunol. 2015;59:700-704. [5]. 30368949. A synergistic role for two predicted inner membrane proteins of Escherichia coli in cell envelope integrity. Mychack A, Amrutha RN, Chung C, Cardenas Arevalo K, Reddy M, Janakiraman A;. Mol Microbiol. 2019;111:317-337. [6]. 33431434. Defects in The First Step of Lipoprotein Maturation Underlie The Synthetic Lethality of Escherichia coli Lacking The Inner Membrane Proteins YciB And DcrB. Mychack A, Janakirama. TRUNCATED at 1650 bytes (from Pfam)
GO Terms:- Date:
- 2024-10-16