Protein Family Models

TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure [1]. This family also contains VIRB2 type IV secretion proteins [2]. This alignment contains two predicted transmembrane helices. [1]. 12160637. Tying rings for sex. Kalkum M, Eisenbrandt R, Lurz R, Lanka E;. Trends Microbiol 2002;10:382-387. [2]. 12421311. The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Schulein R, Dehio C;. Mol Microbiol 2002;46:1053-1067. (from Pfam)

Date:

2024-10-16

TrbC/VirB2 family protein may function a major pilus subunit; similar to type IV secretion system protein PtlA, which is a component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane

Date:

2021-02-01