The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea [1,2,4-6]. There are also eukaryotic relatives of this protein, like the plasma membrane magnesium transporter ALR2 from yeast (Swiss:P43553). This entry also includes related proteins such as the zinc transporter ZntB [6]. [1]. 9775386. The CorA magnesium transporter gene family. Kehres DG, Lawyer CH, Maguire ME;. Microb Comp Genomics 1998;3:151-169. [2]. 9786860. The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore. Smith RL, Szegedy MA, Kucharski LM, Walker C, Wiet RM, Redpath A, Kaczmarek MT, Maguire ME;. J Biol Chem 1998;273:28663-28669. [3]. 12142406. ZntB is a novel Zn2+ transporter in Salmonella enterica serovar Typhimurium. Worlock AJ, Smith RL;. J Bacteriol. 2002;184:4369-4373. [4]. 17619822. The CorA family: structure and function revisited. Niegowski D, Eshaghi S;. Cell Mol Life Sci. 2007;64:2564-2574. [5]. 23425532. Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport. Nordin N, Guskov A, Phua T, Sahaf N, Xia Y, Lu S, Eshaghi H, Eshaghi S;. Biochem J. 2013;451:365-374. [6]. 16598263. Crystal structure of the CorA Mg2+ transporter. Lunin VV, Dobrovetsky E, Khutoreskaya G, Zhang R, Joachimiak A, Doyle DA, Bochkarev A, Maguire ME, Edwards AM, Koth CM;. Nature. 2006;440:833-837. (from Pfam)
GO Terms:- Date:
- 2024-10-16