Protein Family Models

This domain belongs to the periplasmic binding protein superfamily. (from Pfam)

Date:

2024-08-14

Members of this family are the substrate-binding protein of the phosphate ABC transporter as found in Mollicutes genera such as Mycoplasma, Mesoplasma, and Spiroplasma. The most similar sequences outside this family are PtsS in family TIGR02136, but sequence architecture differs considerably. Members of this family are never lipoproteins.

Gene:

ptsS

Date:

2019-09-10

type 2 periplasmic-binding protein (PBP2) is typically comprised of two globular subdomains connected by a flexible hinge; it binds its ligand in the cleft between these domains in a manner resembling a Venus flytrap; similar to the ligand-binding domains found in solute binding proteins that serve as initial receptors in the transport, signal transduction and channel gating; ABC transporter substrate-binding protein functions as the initial receptor in the transport of substrates like aromatic compounds, similar to Rhodopseudomonas palustris Rpa0668 which preferentially binds lignin-derived benzoate derivative compounds

Date:

2017-03-02