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PgaD family protein
This family includes the PgaD protein from E. coli Swiss:P69432. The homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (beta-1,6-GlcNAc; PGA) serves as an adhesin for the maintenance of biofilm structural stability in eubacteria. The pgaABCD operon is required for its synthesis and export. It has been shown that PgaD is essential for this process [2]. [1]. 15090514. The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation. Wang X, Preston JF 3rd, Romeo T;. J Bacteriol. 2004;186:2724-2734. [2]. 18359807. Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine. Itoh Y, Rice JD, Goller C, Pannuri A, Taylor J, Meisner J, Beveridge TJ, Preston JF 3rd, Romeo T;. J Bacteriol. 2008;190:3670-3680. (from Pfam)
poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD
Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937).
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