Protein Family Models for Protein (Select 504381079) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
UI List

Sort by

Default order
Publication Date (up)
Publication Date (down)

Send to:

Choose Destination

File
Clipboard
Collections

Links from Protein

Items: 4

Select item 4200331.

poly(ADP-ribose) glycohydrolase domain-containing protein

Poly(ADP-ribose) glycohydrolase (PARG) hydrolyses the ribose-ribose bonds present in poly(ADP-ribose) (PAR) chains. This entry represents the PARG homologue present in bacteria and fungi. Its structure shows a typical macrodomain folding consisting of a seven-stranded beta-sheet sandwiched between nine alpha-helices [1,2]. [1]. 21892188. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase. Slade D, Dunstan MS, Barkauskaite E, Weston R, Lafite P, Dixon N, Ahel M, Leys D, Ahel I;. Nature. 2011;477:616-620. [2]. 30940816. Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans. Cho CC, Chien CY, Chiu YC, Lin MH, Hsu CH;. Nat Commun. 2019;10:1491. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF021533.5
Method:: HMM

Select item 3964032.

new record, indexing in progress

Family Accession:

Select item 3552133.

new record, indexing in progress

Family Accession:

Select item 496284.

TIGR02452 family protein

Members of this uncharacterized protein family are found in Streptomyces, Nostoc sp. PCC 7120, Clostridium acetobutylicum, Lactobacillus johnsonii NCC 533, Deinococcus radiodurans, and Pirellula sp. for a broad but sparse phylogenetic distibution that at least suggests lateral gene transfer.