Protein Family Models

This region is found at the C-terminus of a group of bacterial PH domains. This region is composed of a helical hairpin that appears to mediate oligomerisation based on the known structure. This elaboration of the bacterial PH domain is only found in Bacillales. (from Pfam)

Date:

2024-08-14

This family contains many bacterial hypothetical proteins. The structures of Swiss:A1SD03, PDB:3hsa, and Swiss:A3QB43, PDB:3dcx, show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response [1]. [1]. 19913036. Bacterial pleckstrin homology domains: a prokaryotic origin for. the PH domain.. Xu Q, Bateman A, Finn RD, Abdubek P, Astakhova T, Axelrod HL,. Bakolitsa C, Carlton D, Chen C, Chiu HJ, Chiu M, Clayton T, Das. D, Deller MC, Duan L, Ellrott K, Ernst D, Farr CL, Feuerhelm J,. Grant JC, Grzechnik A, Han GW, Jaroszewski L, Jin KK, Klock HE,. Knuth MW, Kozbial P, Krishna SS, Kumar A, Marciano D, McMullan. D, Miller MD, Morse AT, Nigoghossian E, Nopakun A, Okach L,. Puckett C, Reyes R, Rife CL, Sefcovic N, Tien HJ, Trame CB, van. den Bedem H, Weekes D, Wooten T, Hodgson KO, Wooley J, Elsliger. MA, Deacon AM, Godzik A, Lesley SA, Wilson IA.. J Mol Biol. 2010 Feb 12;396(1):31-46. Epub 2009 Nov 10. (from Pfam)

Date:

2024-08-14

bacterial Pleckstrin homology (bPH) domain-containing protein may be involved in protein-protein interactions

Date:

2017-03-02