Protein Family Models for Protein (Select 502696941) - Protein Family Models

Select item 4249101.

RecQ family zinc-binding domain-containing protein

This domain is the zinc-binding domain of ATP-dependent DNA helicase RecQ [1-2]. [1]. 14517231. High-resolution structure of the E.coli RecQ helicase catalytic. core.. Bernstein DA, Zittel MC, Keck JL;. EMBO J. 2003;22:4910-4921.. [2]. 19151156. Structure of the human RECQ1 helicase reveals a putative. strand-separation pin.. Pike AC, Shrestha B, Popuri V, Burgess-Brown N, Muzzolini L,. Costantini S, Vindigni A, Gileadi O;. Proc Natl Acad Sci U S A. 2009;106:1039-1044. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF027450.5
Method:: HMM

Select item 4177702.

RQC domain-containing protein

The vast majority of proteins with this DNA-binding domain, called RQC, are RecQ itself, a DNA helicase involved in recombination, replication, and repair. But a few, including WP_003865531 and WP_016764356 represent distinct proteins families with different lengths and currently unknown functions.

GO Terms:

Biological Process:: DNA replication (GO:0006260)

Biological Process:: DNA repair (GO:0006281)

Molecular Function:: 3'-5' DNA helicase activity (GO:0043138)

Date:: 2024-08-14

Family Accession:: NF020939.5
Method:: HMM

Select item 4149163.

DEAD/DEAH box helicase family protein

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: hydrolase activity (GO:0016787)

Date:: 2024-08-14

Family Accession:: NF016724.5
Method:: HMM

Select item 4118844.

DEAD/DEAH box helicase

Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. [1]. 10322435. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and. related families.. de la Cruz J, Kressler D, Linder P;. Trends Biochem Sci 1999;24:192-198.. [2]. 9862990. The DEAD box RNA helicase family in Arabidopsis thaliana.. Aubourg S, Kreis M, Lecharny A;. Nucleic Acids Res 1999;27:628-636. (from Pfam)

GO Terms:

Molecular Function:: nucleic acid binding (GO:0003676)

Molecular Function:: ATP binding (GO:0005524)

Date:: 2024-08-14

Family Accession:: NF012492.5
Method:: HMM

Select item 4117615.

helicase-related protein

The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012493.5
Method:: HMM

Select item 4023666.