Protein Family Models

The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter [3]. [1]. 6301339. Structure and function of H+-ATPase: what we have learned from Escherichia coli H+-ATPase. Kanazawa H, Futai M;. Ann N Y Acad Sci 1982;402:45-64. [2]. 7961438. Bacillus subtilis F0F1 ATPase: DNA sequence of the atp operon and characterization of atp mutants. Santana M, Ionescu MS, Vertes A, Longin R, Kunst F, Danchin A, Glaser P;. J Bacteriol 1994;176:6802-6811. [3]. 12917488. A tenth atp gene and the conserved atpI gene of a Bacillus atp operon have a role in Mg2+ uptake. Hicks DB, Wang Z, Wei Y, Kent R, Guffanti AA, Banciu H, Bechhofer DH, Krulwich TA;. Proc Natl Acad Sci U S A. 2003;100:10213-10218. (from Pfam)

Date:

2024-10-16

F0F1 ATP synthase subunit I may guide the assembly of the membrane sector of the ATPase enzyme complex

Date:

2021-01-12

Produces ATP from ADP in the presence of a proton gradient across the membrane; subunit I associates with the membrane and may be involved with cation translocation

Gene:

atpI

Date:

2020-10-26