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MFS transporter
Fungal trichothecene efflux pump (TRI12)
This family consists of several fungal specific trichothecene efflux pump proteins. Many of the genes involved in trichothecene toxin biosynthesis in Fusarium sporotrichioides are present within a gene cluster.It has been suggested that TRI12 may play a role in F. sporotrichioides self-protection against trichothecenes [1]. [1]. 10485289. TRI12, a trichothecene efflux pump from Fusarium sporotrichioides: gene isolation and expression in yeast. Alexander NJ, McCormick SP, Hohn TM;. Mol Gen Genet 1999;261:977-984. (from Pfam)
MDR family MFS transporter
MDR (multi-drug resistance) family major facilitator superfamily (MFS) transporter confers resistance to specific drugs/toxins through their active efflux from the cell
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