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2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
The ygbB protein is a putative enzyme of deoxy-xylulose pathway (terpenoid biosynthesis) [1]. [1]. 10694574. Biosynthesis of terpenoids: YgbB protein converts. 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to. 2C-methyl-D-erythritol 2,4-cyclodiphosphate.. Herz S, Wungsintaweekul J, Schuhr CA, Hecht S, Luttgen H, Sagner. S, Fellermeier M, Eisenreich W, Zenk MH, Bacher A, Rohdich F;. Proc Natl Acad Sci U S A 2000;97:2486-2490. (from Pfam)
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Members of this family are enzymes which catalyse the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from cytidine triphosphate and 2-C-methyl-D-erythritol 4-phosphate (MEP) [1]. [1]. 10518523. Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids:. YgbP protein of Escherichia coli catalyzes the formation of. 4-diphosphocytidyl-2-C-methylerythritol.. Rohdich F, Wungsintaweekul J, Fellermeier M, Sagner S, Herz S,. Kis K, Eisenreich W, Bacher A, Zenk MH;. Proc Natl Acad Sci U S A. 1999;96:11758-11763. (from Pfam)
Members of this protein family are 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, the IspF protein of the deoxyxylulose (non-mevalonate) pathway of IPP biosynthesis. This protein occurs as an IspDF bifunctional fusion protein in about 20 percent of bacterial genomes.
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