Protein Family Models for Protein (Select 501409471) - Protein Family Models

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Links from Protein

Items: 6

Select item 4151561.

The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance [1]. [1]. 10714982. The Staphylococcus aureus lrgAB operon modulates murein. hydrolase activity and penicillin tolerance.. Groicher KH, Firek BA, Fujimoto DF, Bayles KW;. J Bacteriol 2000;182:1794-1801. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF016088.5
Method:: HMM

Select item 3912052.

new record, indexing in progress

Family Accession:

Select item 3500493.

new record, indexing in progress

Family Accession:

Select item 549114.

LrgB family protein

LrgB family protein similar to Escherichia coli inner membrane protein YohK and to LrgB, a potential membrane protein which is thought to control murein hydrolase activity and penicillin tolerance

Date:: 2018-06-27

Family Accession:: 10013610
Method:: Sparcle

Select item 237315.

CidB/LrgB family autolysis modulator

Date:: 2020-10-26

Family Accession:: NF007983.0
Method:: HMM

Select item 223976.

CidB/LrgB family autolysis modulator

Members of this small but broadly distibuted (Gram-positive, Gram-negative, and Archaeal) family appear to have multiple transmembrane segments. The function is unknown. A homolog, LrgB of Staphylococcus aureus, in the same small superfamily but in an outgroup to this subfamily, is regulated by LytSR and is suggested to act as a murein hydrolase. Of the three paralogous proteins in B. subtilis, one is a full length member of this family, one lacks the C-terminal 60 residues and has an additional 128 N-terminal residues but branches within the family in a phylogenetic tree, and one is closely related to LrgB and part of the outgroup.