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signal recognition particle receptor subunit alpha
Signal peptide binding domain
SRP54-type protein, GTPase domain
This family includes relatives of the G-domain of the SRP54 family of proteins. [1]. 9002525. Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Montoya G, Svensson C, Luirink J, Sinning I;. Nature 1997;385:365-368. (from Pfam)
signal recognition particle protein
signal recognition particle protein such as SRP54, a GTPase involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane; binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes
This model represents Ffh (Fifty-Four Homolog), the protein component that forms the bacterial (and organellar) signal recognition particle together with a 4.5S RNA. Ffh is a GTPase homologous to eukaryotic SRP54 and also to the GTPase FtsY (TIGR00064) that is the receptor for the signal recognition particle.
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