Protein Family Models for Protein (Select 499971218) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Links from Protein

Items: 7

Select item 4152331.

methyltransferase

Members of this family include both N- and O-methyltransferases.

Date:: 2024-10-16

Family Accession:: NF016107.5
Method:: HMM

Select item 4151542.

isoprenylcysteine carboxylmethyltransferase family protein

The isoprenylcysteine o-methyltransferase (EC:2.1.1.100) family carry out carboxyl methylation of cleaved eukaryotic proteins that terminate in a CaaX motif. In Saccharomyces cerevisiae this methylation is carried out by Ste14p, an integral endoplasmic reticulum membrane protein. Ste14p is the founding member of the isoprenylcysteine carboxyl methyltransferase (ICMT) family, whose members share significant sequence homology [1]. [1]. 11451995. Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase family. Romano JD, Michaelis S;. Mol Biol Cell 2001;12:1957-1971. (from Pfam)

GO Terms:

Molecular Function:: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity (GO:0004671)

Biological Process:: C-terminal protein methylation (GO:0006481)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-10-16

Family Accession:: NF016062.5
Method:: HMM

Select item 3921133.

new record, indexing in progress

Family Accession:

Select item 3917104.

new record, indexing in progress

Family Accession:

Select item 3504485.

new record, indexing in progress

Family Accession:

Select item 3498726.

new record, indexing in progress

Family Accession:

Select item 1761247.

methyltransferase family protein

methyltransferase family protein such as methanethiol S-methyltransferase that catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS)