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Items: 10

1.

MerR family transcriptional regulator

GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Biological Process:
regulation of DNA-templated transcription (GO:0006355)
Date:
2024-08-14
Family Accession:
NF024803.5
Method:
HMM
2.

MerR family DNA-binding protein

Members of this family of DNA-binding domains are predominantly found in the prokaryotic transcriptional regulator MerR. They adopt a structure consisting of a core of three alpha helices, with an architecture that is similar to that of the 'winged helix' fold [1]. [1]. 12958362. Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR. Changela A, Chen K, Xue Y, Holschen J, Outten CE, O'Halloran TV, Mondragon A;. Science. 2003;301:1383-1387. (from Pfam)

Date:
2024-10-16
Family Accession:
NF020839.5
Method:
HMM
3.

MerR family DNA-binding transcriptional regulator

GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Biological Process:
regulation of DNA-templated transcription (GO:0006355)
Date:
2024-08-14
Family Accession:
NF012594.5
Method:
HMM
4.
new record, indexing in progress
Family Accession:
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
Family Accession:
7.
new record, indexing in progress
Family Accession:
8.
new record, indexing in progress
Family Accession:
9.
new record, indexing in progress
Family Accession:
10.

Cu(I)-responsive transcriptional regulator

This HMM represents the copper-, silver- and gold- (I) responsive transcriptional activator of the gamma proteobacterial copper efflux system [1]. This protein is a member of the MerR family of transcriptional activators (PF00376) and contains a distinctive pattern of cysteine residues in its metal binding loop, Cys-X7-Cys. This family also lacks a conserved cysteine at the N-terminal end of the dimerization helix which is required for the binding of divalent metals such as zinc; here it is replaced by a serine residue [2].

Gene:
cueR
GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Molecular Function:
DNA-binding transcription factor activity (GO:0003700)
Molecular Function:
copper ion binding (GO:0005507)
Biological Process:
positive regulation of DNA-templated transcription (GO:0045893)
Biological Process:
response to copper ion (GO:0046688)
Date:
2024-05-15
Family Accession:
TIGR02044.1
Method:
HMM

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