Protein Family Models

This family is the guanine nucleotide exchange domain of EF-1 beta and EF-1 delta chains. [1]. 10368288. The solution structure of the guanine nucleotide exchange domain. of human elongation factor 1beta reveals a striking resemblance. to that of EF-Ts from Escherichia coli.. Perez JM, Siegal G, Kriek J, H rd K, Dijk J, Canters GW, Moller. W;. Structure Fold Des 1999;7:217-226. (from Pfam)

Date:

2024-08-14

elongation factor 1-beta promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA

Date:

2021-01-11

EF-1-alpha; functions during elongation stage of protein translation; forms a dimer; associates with EF-1-beta-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-1-alpha

Date:

2020-10-26

This model describes the archaeal translation elongation factor aEF-1 beta. The member from Sulfolobus solfataricus was demonstrated experimentally. It is a dimer that catalyzes the exchange of GDP for GTP on aEF-1 alpha.

Date:

2021-04-27