Protein Family Models for Protein (Select 496266394) - Protein Family Models

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Items: 4

Select item 4196021.

S26 family signal peptidase

This is a family of membrane signal serine endopeptidases which function in the processing of newly-synthesised secreted proteins. Peptidase S26 removes the hydrophobic, N-terminal, signal peptides as proteins are translocated across membranes. The active site residues take the form of a catalytic dyad that is Ser, Lys in subfamily S26A; the Ser is the nucleophile in catalysis, and the Lys is the general base. (from Pfam)

GO Terms:

Molecular Function:: serine-type endopeptidase activity (GO:0004252)

Biological Process:: signal peptide processing (GO:0006465)

Date:: 2024-08-14

Family Accession:: NF021981.5
Method:: HMM

Select item 3975542.

new record, indexing in progress

Family Accession:

Select item 3563903.

new record, indexing in progress

Family Accession:

Select item 487784.

signal peptidase I

This HMM represents signal peptidase I from most archaea, a subunit of the eukaryotic endoplasmic reticulum signal peptidase I complex, and an apparent signal peptidase I from a small number of bacteria. It is related to but does not overlap in hits with TIGR02227, the bacterial and mitochondrial signal peptidase I.

GO Terms: