Protein Family Models

Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus [1,2]. [1]. 1860816. Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica. Michiels T, Vanooteghem JC, Lambert de Rouvroit C, China B, Gustin A, Boudry P, Cornelis GR;. J Bacteriol 1991;173:4994-5009. [2]. 22349221. Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system. Lountos GT, Tropea JE, Waugh DS;. Acta Crystallogr D Biol Crystallogr. 2012;68:201-209. (from Pfam)

Date:

2024-10-16

The FHA (Forkhead-associated) domain is a phosphopeptide binding motif [2]. [1]. 7482699. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Hofmann K, Bucher, P;. Trends Biochem Sci 1995;20:347-349. [2]. 10518219. The FHA domain is a modular phosphopeptide recognition motif. Durocher D, Henckel J, Fersht AR, Jackson SP;. Mol Cell. 1999;4:387-394. [3]. 12564991. Bacterial FHA domains: neglected players in the phospho-threonine signalling game?. Pallen M, Chaudhuri R, Khan A;. Trends Microbiol 2002;10:556-563. (from Pfam)

Date:

2024-10-16

FHA (forkhead-associated) domain-containing protein participates in signal transduction pathways via protein-protein interactions involving recognition of pThr and pTyr phosphopeptides

Date:

2024-11-08