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ureidoglycolate lyase
Ureidoglycolate lyase (EC:4.3.2.3) is one of the enzymes that acts upon ureidoglycolate, an intermediate of purine catabolism, releasing urea [2]. The enzyme has in the past been wrongly assigned to EC:3.5.3.19, enzymes which release ammonia from ureidoglycolate [1]. [1]. 24107613. Ureidoglycolate hydrolase, amidohydrolase, lyase: how errors in biological databases are incorporated in scientific papers and vice versa. Percudani R, Carnevali D, Puggioni V;. Database (Oxford). 2013;2013:bat071. [2]. 19935661. Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Werner AK, Romeis T, Witte CP;. Nat Chem Biol. 2010;6:19-21. (from Pfam)
ureidoglycolate lyase catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate
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