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molybdopterin cofactor-binding domain-containing protein
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
xanthine dehydrogenase molybdopterin binding subunit
xanthine dehydrogenase molybdopterin binding subunit froms a complex with the iron-sulfur and FAD-binding subunits to form a heterotrimeric enzyme that catalyzes the oxidation of hypoxanthine and xanthine to uric acid
Members of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase.
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