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PspC domain-containing protein
This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length. [1]. 1712397. Characterization and sequence of the Escherichia coli stress-induced psp operon. Brissette JL, Weiner L, Ripmaster TL, Model P;. J Mol Biol 1991;220:35-48. (from Pfam)
envelope stress response membrane protein PspC
envelope stress response membrane protein PspC is involved in transcription regulation; the pspC gene is part of phage shock protein (psp) operon that may play a role in the competition for survival under nutrient- or energy-limited conditions
All members of this protein family are the phage shock protein PspC. These proteins contain a PspC domain, as do other members of the larger family of proteins described by Pfam model PF04024. The phage shock regulon is restricted to the Proteobacteria and somewhat sparsely distributed there. It is expressed, under positive control of a sigma-54-dependent transcription factor, PspF, which binds and is modulated by PspA. Stresses that induce the psp regulon include phage secretin overexpression, ethanol, heat shock, and protein export defects.
Activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock
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