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Links from Protein

Items: 6

1.

succinylglutamate desuccinylase/aspartoacylase family protein

This family includes Succinylglutamate desuccinylase EC:3.1.-.- that catalyses the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway. The family also include aspartoacylase EC:3.5.1.15 which cleaves acylaspartate into a fatty acid and aspartate. Mutations in Swiss:P45381 lead to Canavan disease disease [1]. This family is probably structurally related to Pfam:PF00246 (Bateman A pers. obs.). [1]. 8252036. Cloning of the human aspartoacylase cDNA and a common missense mutation in Canavan disease. Kaul R, Gao GP, Balamurugan K, Matalon R;. Nat Genet 1993;5:118-123. (from Pfam)

GO Terms:
Molecular Function:
hydrolase activity, acting on ester bonds (GO:0016788)
Date:
2024-10-16

Family Accession:
NF016817.5
Method:
HMM

2.

M14 family zinc carboxypeptidase

GO Terms:
Molecular Function:
metallocarboxypeptidase activity (GO:0004181)
Biological Process:
proteolysis (GO:0006508)
Molecular Function:
zinc ion binding (GO:0008270)
Date:
2024-08-14

Family Accession:
NF012471.5
Method:
HMM

3.
new record, indexing in progress
Family Accession:
4.
new record, indexing in progress
Family Accession:
5.
new record, indexing in progress
Family Accession:
6.
new record, indexing in progress
Family Accession:
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