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Links from Protein

Items: 5

1.

L-histidine N(alpha)-methyltransferase

The mycobacterial members of this family are expressed from part of the ergothioneine biosynthetic gene cluster. EGTD is the histidine methyltransferase that transfers three methyl groups to the alpha-amino moiety of histidine, in the first stage of the production of this histidine betaine derivative that carries a thiol group attached to the C2 atom of an imidazole ring [1]. [1]. 20420449. In vitro reconstitution of Mycobacterial ergothioneine. biosynthesis.. Seebeck FP;. J Am Chem Soc. 2010;132:6632-6633. (from Pfam)

Date:
2024-08-14
Family Accession:
NF021530.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

L-histidine N(alpha)-methyltransferase

This model represents a distinct set of uncharacterized proteins found in the bacteria. Analysis by PSI-BLAST shows remote sequence homology to methyltransferases

Gene:
egtD
GO Terms:
Molecular Function:
dimethylhistidine N-methyltransferase activity (GO:0030745)
Biological Process:
ergothioneine biosynthetic process (GO:0052699)
Date:
2021-04-27
Family Accession:
TIGR03438.1
Method:
HMM
5.

L-histidine N(alpha)-methyltransferase

L-histidine N(alpha)-methyltransferase catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine

Date:
2024-09-12
Family Accession:
11468194
Method:
Sparcle
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