Protein Family Models

This domain is related to Pfam:PF00549 and adopts a flavodoxin fold [1]. [1]. 26787904. Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer. Weisse RH, Faust A, Schmidt M, Schonheit P, Scheidig AJ;. Proc Natl Acad Sci U S A. 2016;113:E519-E528. (from Pfam)

Date:

2024-10-16

This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity. (from Pfam)

Date:

2024-08-14

This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer. [1]. 11781092. Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase. Fraser ME, Joyce MA, Ryan DG, Wolodko WT;. Biochemistry. 2002;41:537-546. (from Pfam)

Date:

2024-10-16

This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. (from Pfam)

Date:

2024-08-14

This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. [1]. 8144675. The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution. Wolodko WT, Fraser ME, James MN, Bridger WA;. J Biol Chem 1994;269:10883-10890. (from Pfam)

Date:

2024-10-16

acetate--CoA ligase family protein similar to ADP-forming acetate--CoA ligase that catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate

Date:

2025-01-03