Protein Family Models for Protein (Select 492476669) - Protein Family Models

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Items: 4

Select item 4291741.

DUF4842 domain-containing protein

This domain is found on the C-terminal of large number of uncharacterized proteins with broad phylogenetic distribution, which includes human gut Bacteroides, g-proteobacteria (Vibrio and Shewanella) and also spirochetes from Leptospira genus. Solved structure of Bacteroides ovatus protein BACOVA_00967 shows a large beta barrel with an immunoglobulin-like fold and significant structural similarity to collagen-binding domain of adhesin from S. aureus (1amx), but with several additional long loops and secondary structure elements. Function of this domain is unknown. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF027456.5
Method:: HMM

Select item 4031502.

new record, indexing in progress

Family Accession:

Select item 3657373.

new record, indexing in progress

Family Accession:

Select item 780954.

LruC domain-containing protein

This domain is abundant in the Leptospira, in Bacteroides, and in Vibrio (three widely separated lineages). Most members have plausible lipoprotein signal peptides, including lipoprotein LruC from Leptospira interrogans and BACOVA_00967, from Bacteroides ovatus, with a solved crystal structure. Note that the C-terminal region of Pfam model PF13448 (length 83) matches the N-terminal region of some members of this domain (length 243).