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CrcB family protein
CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance [1,2]. [1]. 8844142. Overproduction of three genes leads to camphor resistance and chromosome condensation in Escherichia coli. Hu KH, Liu E, Dean K, Gingras M, DeGraff W, Trun NJ;. Genetics 1996;143:1521-1532. [2]. 12904550. Phenotypic characterization of overexpression or deletion of the Escherichia coli crcA, cspE and crcB genes. Sand O, Gingras M, Beck N, Hall C, Trun N;. Microbiology. 2003;149:2107-2117. (from Pfam)
fluoride efflux transporter FluC
fluoride efflux transporter FluC is fluoride-specific ion channel which Important for reducing fluoride concentration in the cell to reduce its toxicity
fluoride efflux transporter CrcB
CrcB was previously annotated as camphor resistance protein, and linked to chromosome condensation. However, it confers resistance to fluoride ion, by acting as an efflux transporter, and usually is preceded by a fluoride-responsive riboswitch.
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