Protein Family Models for Protein (Select 491954888) - Protein Family Models

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Items: 4

Select item 4128651.

1-acyl-sn-glycerol-3-phosphate acyltransferase

This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function [1]. This family also includes tafazzin Swiss:Q16635, the Barth syndrome gene [2]. [1]. 9259571. Barth syndrome may be due to an acyltransferase deficiency. Neuwald AF;. Curr Biol 1997;7:465-466. [2]. 8630491. A novel X-linked gene, G4.5. is responsible for Barth syndrome. Bione S, D'Adamo P, Maestrini E, Gedeon AK, Bolhuis PA, Toniolo D;. Nat Genet 1996;12:385-389. (from Pfam)

GO Terms:

Molecular Function:: acyltransferase activity (GO:0016746)

Date:: 2024-10-16

Family Accession:: NF013702.5
Method:: HMM

Select item 3902232.

new record, indexing in progress

Family Accession:

Select item 3472863.

new record, indexing in progress

Family Accession:

Select item 910704.

lysophospholipid acyltransferase family protein

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid; 1-acyl-sn-glycerol-3-phosphate acyltransferase, for example, converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position by utilizing either acyl-CoA or acyl-ACP as the fatty acyl donor;