Protein Family Models for Protein (Select 491524265) - Protein Family Models

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Items: 5

Select item 4123811.

Trp family transcriptional regulator

This protein binds to tryptophan and represses transcription of the Trp operon. [1]. 3419502. Crystal structure of trp repressor/operator complex at atomic resolution. Otwinowski Z, Schevitz RW, Zhang RG, Lawson CL, Joachimiak A, Marmorstein RQ, Luisi BF, Sigler PB. Nature 1988;335:321-329. (from Pfam)

GO Terms:

Molecular Function:: DNA-binding transcription factor activity (GO:0003700)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Date:: 2024-10-16

Family Accession:: NF013531.5
Method:: HMM

Select item 3893772.

new record, indexing in progress

Family Accession:

Select item 3478133.

new record, indexing in progress

Family Accession:

Select item 1418524.

trp operon repressor

Members of this family are the trp operon repressor TrpR, as the term is used in Escherchia coli and related species. When complexed with L-tryptophan, TrpR binds the operator region of the trp operon and prevents the initiation of transcription.