U.S. flag

An official website of the United States government

Links from Protein

Items: 5

1.

7-cyano-7-deazaguanine synthase

This family of proteins participate in the biosynthesis of 7-carboxy-7-deazaguanine. They catalyse the conversion of 7-deaza-7-carboxyguanine to preQ0 [1-3]. [1]. 14660578. Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine. Reader JS, Metzgar D, Schimmel P, de Crecy-Lagard V;. J Biol Chem. 2004;279:6280-6285. [2]. 16199558. Genetic analysis identifies a function for the queC (ybaX) gene product at an initial step in the queuosine biosynthetic pathway in Escherichia coli. Gaur R, Varshney U;. J Bacteriol. 2005;187:6893-6901. [3]. 19354300. The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of PreQ(0) from guanosine 5'-triphosphate in four steps. McCarty RM, Somogyi A, Lin G, Jacobsen NE, Bandarian V;. Biochemistry. 2009;48:3847-3852. [4]. 18491386. Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis. Cicmil N, Huang RH;. Proteins. 2008;72:1084-1088. (from Pfam)

Date:
2024-10-16
Family Accession:
NF018242.5
Method:
HMM
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

7-cyano-7-deazaguanine synthase QueC

Catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis

Gene:
queC
Date:
2020-10-26
Family Accession:
NF008317.0
Method:
HMM
5.

7-cyano-7-deazaguanine synthase QueC

Members of this protein family are QueC, involved in synthesizing pre-Q0 from GTP en route to tRNA modification with queuosine. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In Rhizobium meliloti, the gene was designated exsB, possibly because of polar effects on exsA expression in a shared polycistronic mRNA. In Arthrobacter viscosus, the homologous gene was designated ALU1 and was associated with an aluminum tolerance phenotype.

Gene:
queC
GO Terms:
Biological Process:
queuosine biosynthetic process (GO:0008616)
Date:
2021-04-27
Family Accession:
TIGR00364.1
Method:
HMM

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center
External link. Please review our privacy policy.