Protein Family Models for Protein (Select 491046970) - Protein Family Models

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Links from Protein

Items: 7

Select item 4118781.

This family includes a diverse range of phosphoesterases [1], including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD Swiss:P13457 or yeast MRE11 Swiss:P32829. The most conserved regions in this superfamily centre around the metal chelating residues. [1]. 9685491. Phosphoesterase domains associated with DNA polymerases of diverse origins. Aravind L, Koonin EV;. Nucleic Acids Res 1998;26:3746-3752. (from Pfam)

GO Terms:

Molecular Function:: hydrolase activity (GO:0016787)

Date:: 2024-10-16

Family Accession:: NF012376.5
Method:: HMM

Select item 3883792.

new record, indexing in progress

Family Accession:

Select item 3570353.

new record, indexing in progress

Family Accession:

Select item 3471024.

new record, indexing in progress

Family Accession:

Select item 1722435.

symmetrical bis(5'-nucleosyl)-tetraphosphatase

Hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP

GO Terms:

Molecular Function:: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity (GO:0008803)

Date:: 2021-08-11

Family Accession:: NF001204.0
Method:: HMM

Select item 864086.

diadenosine tetraphosphatase

diadenosine tetraphosphatase catalyzes the hydrolysis of P1,P4-bis(5'-adenosyl) tetraphosphate to yield ADP

Date:: 2017-02-03

Family Accession:: 11478265
Method:: Sparcle

Select item 218757.

bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH

Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a metabolite whose levels link to stress conditions. It is hydrolyzed to two ADP by this enzyme. Note that Ap4A cleavage can be performed instead by HD (TIGR00488) and Nudix family hydrolases. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase.