Protein Family Models

This family includes cytochrome b561 and related proteins, in addition to the nickel-dependent hydrogenases b-type cytochrome subunit. Cytochrome b561 is a secretory vesicle-specific electron transport protein. It is an integral membrane protein, that binds two heme groups non-covalently. This is a prokaryotic family. Members of the 'eukaryotic cytochrome b561' family can be found in Pfam: PF03188. (from Pfam)

Date:

2024-08-14

Nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase

Gene:

fdnI

Date:

2021-03-11

This model represents the gamma chain of the gamma proteobacteria (and Aquifex aolicus) formate dehydrogenase. This subunit is integral to the cytoplasmic membrane, consisting of 4 transmembrane helices, and receives electrons from the beta subunit. The entire E. coli formate dehydrogenase N (nitrate-inducible form) has been crystallized [1]. The gamma subunit contains two cytochromes, heme b(P) and heme b(C) near the periplasmic and cytoplasmic sides of the membrane respectively. The electron acceptor quinone binds at the cytoplasmic heme histidine ligand. NiFe-hydrogenase and thiosulfate reductase contain homologous gamma subunits, and these can be found scoring in the noise of this model.

Date:

2021-04-27

formate dehydrogenase-N subunit gamma is the cytochrome b556 component of the formate dehydrogenase-N (nitrate-inducible), and also contains a menaquinone reduction site that receives electrons from the beta subunit (FdnH), through its hemes

Date:

2020-11-20