Protein Family Models

The TerB_N domain is found N-terminal to TerB, and TerB_C containing proteins [1]. It has a predominantly alpha-helical structure and contains an absolutely conserved glutamate [1]. The presence of a conserved acidic residue suggests that it might chelate metal like TerB [1]. These proteins occur in a two-gene operon containing an AAA+ ATPase and SF-II DNA helicase suggesting a role in stress-response or phage defence [1]. [1]. 23044854. Ter-dependent stress response systems: novel pathways related to metal sensing, production of a nucleoside-like metabolite, and DNA-processing. Anantharaman V, Iyer LM, Aravind L;. Mol Biosyst. 2012;8:3142-3165. (from Pfam)

Date:

2024-10-16

TerB-C occurs C-terminal of TerB in TerB-N containing proteins. This domain displays multiple conserved acidic residues (TerBC) [1]. The presence of conserved acidic residues in both TerB-N and TerB-C suggests that they, like the TerB domain, might also chelate metals. These two domains may also occur together in the same protein independently of TerB [1]. [1]. 23044854. Ter-dependent stress response systems: novel pathways related to metal sensing, production of a nucleoside-like metabolite, and DNA-processing. Anantharaman V, Iyer LM, Aravind L;. Mol Biosyst. 2012;8:3142-3165. (from Pfam)

Date:

2024-10-16

This family contains the TerB tellurite resistance proteins from a a number of bacteria. [1]. 3049247. The nucleotide sequence of a plasmid determinant for resistance to tellurium anions. Jobling MG, Ritchie DA;. Gene 1988;66:245-258. [2]. 10069007. In vivo and in vitro cloning and phenotype characterization of tellurite resistance determinant conferred by plasmid pTE53 of a clinical isolate of Escherichia coli. Burian J, Tu N, Kl'ucar L, Guller L, Lloyd-Jones G, Stuchlik S, Fejdi P, Siekel P, Turna J;. Folia Microbiol (Praha) 1998;43:589-599. (from Pfam)

Date:

2024-10-16

protein containing domains TerB_N, terB, and TerB_C

Date:

2017-03-02