Protein Family Models

All of these members have the ability to catalyse the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond. [1]. 8917447. Two-dimensional 1H-NMR of transmembrane peptides from. Escherichia coli phosphatidylglycerophosphate synthase in. micelles.. Morein S, Trouard TP, Hauksson JB, Rilfors L, Arvidson G,. Lindblom G;. Eur J Biochem 1996;241:489-497. (from Pfam)

Date:

2024-08-14

CDP-alcohol phosphatidyltransferase family protein catalyzes the transfer of a substituted phosphate group from a cytidine-5'-diphosphate-linked donor to an alcohol acceptor, an essential reaction in the biosynthesis of phospholipids

Date:

2019-02-13

Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.

Gene:

pgsA

Date:

2024-05-30