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NYN domain-containing protein
This family consists of bacterial proteins related to YacP. This family is uncharacterised functionally, but it has been suggested that these proteins are nucleases due to them containing a NYN domain. NYN (for N4BP1, YacP-like Nuclease) domains were discovered by Anantharaman and Aravind [1]. Based on gene neighborhoods it was suggested that the bacterial YacP proteins interact with the Ribonuclease III and TrmH methylase in a processome complex that catalyzes the maturation of rRNA and tRNA [1]. [1]. 17114934. The NYN Domains: Novel Predicted RNAses with a PIN Domain-Like. Fold.. Anantharaman V, Aravind L;. RNA Biol. 2006; [Epub ahead of print] (from Pfam)
uncharacterized YacP-like NYN domain-containing protein may function as a nuclease
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